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John and jane are planning a family, but each has a brother who has sickle-cell disease, so they are concerned that their children may develop sickle-cell disease. neither john nor jane nor their respective parents have the disease. they consult a genetic counselor who tells them that __________.

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The answer would be: it's possible that none of their children will have the disease, but blood tests on them both will be required to make sure

Sickle-cell disease is a disease that affects red blood cells that inherited in an autosomal recessive pattern. It is possible to get the disease from both normal phenotype parent if they both are homozygotes. To make sure, a blood test will be needed,