The primary source of energy for cells and an essential component of aerobic respiration is the citric acid cycle.
It is referred to as the Krebs or citric acid cycle. The cycle converts the acetyl coenzyme A (acetyl CoA) chemical energy into nicotinamide adenine dinucleotide (NADH) reducing force. The TCA cycle is a component of the broader glucose metabolism, which involves the oxidation of glucose to produce pyruvate, which is then further oxidized and enters the TCA cycle as acetyl-CoA.
The cycle's half of intermediates also serves as the starting point for pathways that lead to significant molecules such as fatty acids, amino acids, or porphyrins. The integrity of the cycle is compromised, and the cycle ceases to operate if any of these intermediates are so diverted. Only if anaplerotic (refilling) processes can replace the diverted intermediate or a subsequent intermediate that leads to oxaloacetate can vital energy production be restarted.
Hence, citric acid cycle require multiple enzyme to trap energy in molecular bond.
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