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protective antibodies generated in response to influenza virus bind to ___ of the viral envelope. group of answer choices hemagglutinin and neuraminidase polysaccharides variable surface glycoproteins gp41 and gp120

Respuesta :

Protective antibodies generated in response to influenza virus bind hemagglutinin and neuraminidase to  of the viral envelope.

How does this occur?

Influenza Hemagglutinin (HA) and neuraminidase (NA), two surface glycoproteins found on virions, each have opposing roles. While NA cleaves terminal sialic acids, releasing virions to finish the infectious cycle, HA attaches virions to cells by attaching to terminal sialic acid residues on glycoproteins/glycolipids to start the infectious cycle. Experimental animals can be shielded from IAV pathogenesis by antibodies specific for HA or NA, but this antigenic diversity in the target epitopes reduces the efficiency of the vaccination in humans.

Therefore, hemagglutinin and neuraminidase is the correct answer.

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