Membranes consist of many different types of fatty acids, which confer different properties, including membrane fluidity. Which of the following fatty acids is the LEAST adaptive to maintaining a fluid membrane at cold temperatures?
a)Myristoleic CH3(CH2)3CH=CH(CH2)7COOH
b)Arachidonic CH3(CH2)4CH=CHCH2CH=CHCH2CH=CHCH2CH=CH(CH2)3COOH
c) Caprylic CH3(CH2)6COOH
d) Linoleic CH3(CH2)4CH=CHCH2CH=CH(CH2)7COOH

Respuesta :

The correct answer is Myristoleic CH3(CH2)3CH=CH(CH2)7COOH

Factors affecting membrane fluidity are:

  1. The mosaic structure: The essential lipids and proteins are independent but loosely bound molecules that are present in the membrane.
  2. The phospholipids:
  • The phospholipid tails' fatty acids are in their saturated form, which is devoid of double bonds between nearby carbon atoms and saturated with attached hydrogen atoms. As a result, the tails are mostly straight.
  • Unsaturated fatty acids, in comparison, do not have the greatest amount of hydrogen atoms, but they do include some double bonds between nearby carbon atoms; a double bond causes the string of carbons to bend by around 30 degrees.
  • Therefore, if straight-tailed saturated fatty acids are squeezed by lowering temperatures, they press in on each other to create a dense and reasonably rigid membrane.
  • When unsaturated fatty acids are squeezed, the "kinks" in their tails push nearby phospholipid molecules apart, preserving some distance between them.
  • At temperatures where membranes containing saturated fatty acid tails in their phospholipids would "freeze" or "solidify," this "elbow room" aids in maintaining fluidity in the membrane.
  • In a chilly climate, the relative fluidity of the membrane is crucial. Membranes made primarily of saturated fatty acids are often compressed in a cold environment, becoming less fluid and more prone to rupturing.

Thus, the correct answer is Myristoleic.

Learn more about membrane fluidity here:

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