Overload training that is of a high intensity with limited rest periods would most likely lead to increased levels of testosterone, insulin-like growth factors, and growth hormone.
The integrated communication of numerous physiological systems that control cellular growth and development is substantially facilitated by hormones. Three important hormones—testosterone, the growth hormone superfamily, and the insulin-like growth factor (IGF) superfamily—are regarded as the "anabolic giants" in cellular growth and repair, though the precise hormonal influence must be taken into account in the context of the entire endocrine system and its relationship with other physiological systems. Glucocorticoids, particularly cortisol, must also be taken into account in addition to these anabolic hormones because they frequently have a profoundly opposing effect on human skeletal muscle anabolism.
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