During strenuous exercise, the NADH formed in the glyceraldehyde 3-phosphate dehydrogenase reaction in skeletal muscle must be reoxidized to NAD if glycolysis is to continue. The most important reaction involved in the reoxidation of NADH is:

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13-07-2022
Chemistry

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During strenuous exercise, the NADH formed in the glyceraldehyde 3-phosphate dehydrogenase reaction in skeletal muscle must be reoxidized to NAD if glycolysis is to continue. The most important reaction involved in the reoxidation of NADH is:

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barmansuraj489 barmansuraj489 · Answer 1 · 2022-07-19T04:24:27+02:00

The most important reaction involved in the reoxidation of NADH is Pyruvate → lactate

Two ATP were generated as a net result of glycolysis, two NAD+ were converted to two NADH + H+, and two glucose molecules were divided into two pyruvate molecules.

Pyruvate will go through a process called fermentation when oxygen is absent.

The NADH + H+ from glycolysis will be recycled back to NAD+ during fermentation, allowing glycolysis to proceed.

NAD+ is converted during the glycolysis process into NADH + H+.

Glycolysis cannot proceed without the presence of NAD+.

The NADH produced during glycolysis will be oxidised to create new NAD+ during aerobic respiration, when it will be used once more in glycolysis.

Pyruvate will undergo oxidation in the absence of oxygen or if an organism is unable to engage in aerobic respiration.

Hence The most important reaction involved in the reoxidation of NADH is Pyruvate → lactate

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