Answer:
The recommended dose of paracetamol for adults and children 12 years and over is 500 to 1000mg every four to six hours as necessary, with a maximum of 4000mg in any 24 hour period.
Serious toxicity may occur in patients ingesting more than 150 mg/kg in any 24-hour period. Rarely, toxicity can occur with ingestions between 75 and 150 mg/kg in any 24-hour period.
