How would a drug that blocks acetylcholine release affect muscle contraction? How would a drug that blocks acetylcholine release affect muscle contraction? The strength of contraction would increase. Contraction would be slowed. The speed of contraction would increase. Contraction would be prevented.

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Answer: Contraction would be prevented

Explanation: Acetylcholine is necessary for skeletal muscles contraction, a type of stiated muscle that is involved in voluntary movement. This neurotransmitter enables the formation of cross-bridges between myosin and action filaments, required for muscle contraction. Thus, due to the interference in the cross-bridge formation, a drug that blocks acetylcholine release will prevent muscle contraction.