The presence of Auer rods in the cytoplasm of cells rules out _________
A) ALL
B) AML
C) Myelodysplastic syndrome
D) Acute promyelocytic leukemia
E) None of the above
ALL (acute lymphoblastic leukemia) is a blood cancer where there is an abnormal proliferation of the immature white blood cells called lymphocytes in the bone marrow.
Auer rods are the cytoplasmic inclusions that are crystalline that are made up of lysosomes that are fused and are enriched with lysosomal enzymes.
These are rods are formed in the myeloid blast cells in case of AML, myelodysplastic syndromes, and Acute promyelocytic leukemia.
The Auer rods are not formed during ALL and thus, their presence rules out that the person might be suffering from ALL.
