Therapeutic equivalence of a generic drug product with an innovator drug is assumed when the following conditions are met:
I. They are approved as safe and effective
II. They are pharmaceutical equivalents and bioequivalents
III. They are adequately labelled
IV. They are manufactured in compliance with current good manufacturing practice regulations
V. They have the same time.

Which of the following conditions must be met for therapeutic equivalence?
A. I, II and III
B. II, III and IV
C. III, IV and V
D. I, II, III and IV
E. I, II, III, IV and V
1) I, II and III
2) II, III and IV
3) III, IV and V
4) I, II, III and IV
5) I, II, III, IV and V