- Objective: Illustrate storage, expression and transmission of genetic information that result in observable patterns of inheritance. ssessment (17points possible): Sickle Cell Anemia Pedigree Ickle Cell Disease is a recessive trait (h). Normal Hemoglobin is dominant(H). Shaded shapes are atfected by sickle Cell Disease. Ise your knowledge of Pedigrees and Inheritance Patterns to: 1. Re-draw this Pedigree 2. Label the Genotype (with respect to their alleles for the Hemoglobin gene) of each person on this Pedigree. Some individuals may have more than 1 possible Genotype. Please list all possibilities. Use the following genotypes:HH, Hh and/or hh. 3. What term from Mendelian Genetics would be used to describe the genotype of theF1couple on the Left of this Pedigree? 4. What term from Mendelian Genetics would be used to describe the genotype of theF1couple on the Right of this Pedigree? 5. If theF2female on the far right of this Pedigree marries a male who is Heterozygous for the Sickle Cell allele, what is the probability their children will have Sickle Cell Disease?